rs121434569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
With the advent of third generation TKIs that potentially target T790M, improvement in clinical outcome is documented in patients with NSCLCs.
|
28642172 |
2017 |
rs121434569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
With limited treatment options available in this setting, osimertinib is an important option in adult patients with advanced EGFR T790M-positive NSCLC.
|
28710746 |
2017 |
rs1057519847
|
|
|
0.800 |
GeneticVariation |
BEFREE |
While no significant difference in OS was observed between EGFR exon 19 deletion and L858R mutation, EGFR exon 19 deletion was predictive of longer PFS following EGFR TKI treatment in patients with advanced NSCLC.
|
21725039 |
2011 |
rs1057519848
|
|
|
0.800 |
GeneticVariation |
BEFREE |
While no significant difference in OS was observed between EGFR exon 19 deletion and L858R mutation, EGFR exon 19 deletion was predictive of longer PFS following EGFR TKI treatment in patients with advanced NSCLC.
|
21725039 |
2011 |
rs121434568
|
|
|
0.800 |
GeneticVariation |
BEFREE |
While no significant difference in OS was observed between EGFR exon 19 deletion and L858R mutation, EGFR exon 19 deletion was predictive of longer PFS following EGFR TKI treatment in patients with advanced NSCLC.
|
21725039 |
2011 |
rs1057519847
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We were able to identify EGFR mutations in NSCLC effusion and CSF with a sensitivity of 100% (5/5) using the anti-delE746-A750 antibody and 100% (8/8) using the anti-L858R antibody.
|
21444121 |
2011 |
rs1057519848
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We were able to identify EGFR mutations in NSCLC effusion and CSF with a sensitivity of 100% (5/5) using the anti-delE746-A750 antibody and 100% (8/8) using the anti-L858R antibody.
|
21444121 |
2011 |
rs121434568
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We were able to identify EGFR mutations in NSCLC effusion and CSF with a sensitivity of 100% (5/5) using the anti-delE746-A750 antibody and 100% (8/8) using the anti-L858R antibody.
|
21444121 |
2011 |
rs1057519847
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We were able to identify EGFR mutations in NSCLC tumor samples immunohistochemically with a sensitivity of 79% using the anti-delE746-A750 antibody and 83% using the anti-L858R antibody.
|
20423982 |
2010 |
rs1057519848
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We were able to identify EGFR mutations in NSCLC tumor samples immunohistochemically with a sensitivity of 79% using the anti-delE746-A750 antibody and 83% using the anti-L858R antibody.
|
20423982 |
2010 |
rs121434568
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We were able to identify EGFR mutations in NSCLC tumor samples immunohistochemically with a sensitivity of 79% using the anti-delE746-A750 antibody and 83% using the anti-L858R antibody.
|
20423982 |
2010 |
rs1057519847
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We used this method in a survey of 73 non-small cell lung cancer (NSCLC) samples, detecting 14 mutant samples of E746_A750del and 12 mutant samples of L858R.
|
21439672 |
2011 |
rs1057519848
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We used this method in a survey of 73 non-small cell lung cancer (NSCLC) samples, detecting 14 mutant samples of E746_A750del and 12 mutant samples of L858R.
|
21439672 |
2011 |
rs121434568
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We used this method in a survey of 73 non-small cell lung cancer (NSCLC) samples, detecting 14 mutant samples of E746_A750del and 12 mutant samples of L858R.
|
21439672 |
2011 |
rs121434569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We used HCC827 and PC-9, which are NSCLC cell lines harboring EGFR exon 19 deletions, and gefitinib-resistant sublines derived from the same cell lines with T790M mutation, MET amplification or stem-cell like properties.
|
25607753 |
2015 |
rs121434569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We used four NSCLC cell lines-A549 (wild-type EGFR), H1650 (mutant EGFR; del E746_A750), H1975 (mutant EGFR; L858R, T790M) and H3255 (mutant EGFR; L858R)-and one epidermoid carcinoma cell line, A431 (wild-type EGFR).
|
24583857 |
2014 |
rs1057519847
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We used four NSCLC cell lines-A549 (wild-type EGFR), H1650 (mutant EGFR; del E746_A750), H1975 (mutant EGFR; L858R, T790M) and H3255 (mutant EGFR; L858R)-and one epidermoid carcinoma cell line, A431 (wild-type EGFR).
|
24583857 |
2014 |
rs1057519848
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We used four NSCLC cell lines-A549 (wild-type EGFR), H1650 (mutant EGFR; del E746_A750), H1975 (mutant EGFR; L858R, T790M) and H3255 (mutant EGFR; L858R)-and one epidermoid carcinoma cell line, A431 (wild-type EGFR).
|
24583857 |
2014 |
rs121434568
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We used four NSCLC cell lines-A549 (wild-type EGFR), H1650 (mutant EGFR; del E746_A750), H1975 (mutant EGFR; L858R, T790M) and H3255 (mutant EGFR; L858R)-and one epidermoid carcinoma cell line, A431 (wild-type EGFR).
|
24583857 |
2014 |
rs121434569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We used ddPCR to assess the utility of measuring plasma concentrations of common epidermal growth factor receptor (EGFR) mutations (L858R, exon 19 deletion, and T790M) in 57 non-small cell lung cancer (NSCLC) patients treated with EGFR tyrosine kinase inhibitors (EGFR-TKIs).
|
28061461 |
2017 |
rs1057519847
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We used ddPCR to assess the utility of measuring plasma concentrations of common epidermal growth factor receptor (EGFR) mutations (L858R, exon 19 deletion, and T790M) in 57 non-small cell lung cancer (NSCLC) patients treated with EGFR tyrosine kinase inhibitors (EGFR-TKIs).
|
28061461 |
2017 |
rs1057519848
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We used ddPCR to assess the utility of measuring plasma concentrations of common epidermal growth factor receptor (EGFR) mutations (L858R, exon 19 deletion, and T790M) in 57 non-small cell lung cancer (NSCLC) patients treated with EGFR tyrosine kinase inhibitors (EGFR-TKIs).
|
28061461 |
2017 |
rs121434568
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We used ddPCR to assess the utility of measuring plasma concentrations of common epidermal growth factor receptor (EGFR) mutations (L858R, exon 19 deletion, and T790M) in 57 non-small cell lung cancer (NSCLC) patients treated with EGFR tyrosine kinase inhibitors (EGFR-TKIs).
|
28061461 |
2017 |
rs121913465
|
|
|
0.740 |
GeneticVariation |
BEFREE |
We used a natural language search program to search our electronic medical record system and every EGFR mutation analysis of patients with NSCLC treated at Mayo Clinic that was performed in our Department of Molecular Genetics to identify patients with EGFR S768I mutation.
|
27211795 |
2016 |
rs397517108
|
|
|
0.740 |
GeneticVariation |
BEFREE |
We used a natural language search program to search our electronic medical record system and every EGFR mutation analysis of patients with NSCLC treated at Mayo Clinic that was performed in our Department of Molecular Genetics to identify patients with EGFR S768I mutation.
|
27211795 |
2016 |